Tdap vaccination during pregnancy to reduce pertussis infection in young infants.
نویسندگان
چکیده
QUESTION What is the basis for the new recommendations to vaccinate pregnant women against pertussis after the first trimester? ANSWER There have been outbreaks of epidemic proportions of pertussis, mostly among young infants who have not received sufficient passive immunity from their mothers. This strategy of vaccination during pregnancy aims at stopping these life-threatening epidemics.
منابع مشابه
Pregnancy dose Tdap and postpartum cocooning to prevent infant pertussis: a decision analysis.
BACKGROUND Infants <2 months of age are at highest risk of pertussis morbidity and mortality. Until recently, the US Advisory Committee on Immunization Practices (ACIP) recommended protecting young infants by "cocooning" or vaccination of postpartum mothers and other close contacts with tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis, adsorbed (Tdap) booster vaccine. ACIP rec...
متن کاملTdap Vaccination Coverage During Pregnancy — Selected Sites, United States, 2006–2015
Tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis (Tdap) vaccine is recommended during the third trimester of each pregnancy to provide protection to newborns, who are at risk for pertussis-related morbidity and mortality (1). As part of its case-control surveillance study of medications and birth defects, the Birth Defects Study of the Slone Epidemiology Center at Boston Unive...
متن کاملInfant outcomes after exposure to Tdap vaccine in pregnancy: an observational study
OBJECTIVE Pertussis vaccination during pregnancy has recently been recommended in both the USA and UK to prevent pertussis infection in infants. While there are no apparent safety concerns about the administration of Tdap vaccine during pregnancy, there is only limited safety data available. We aimed to closely monitor infants exposed to Tdap during pregnancy to look for any adverse outcomes th...
متن کاملEffectiveness of Vaccination During Pregnancy to Prevent Infant Pertussis.
BACKGROUND Vaccination against pertussis during pregnancy is recommended to protect newborns, yet there is limited information about the effectiveness of maternal tetanus toxoid, reduced diphtheria toxoid, acellular pertussis (Tdap) vaccine before the first infant dose of diphtheria, tetanus and acellular pertussis (DTaP) vaccine and during the first year of life in infants who have received DT...
متن کاملPertussis among the youngest infants in California: Evaluating the effectiveness of prenatal Tdap vaccination and identifying infants at greatest risk of disease by
Background: Most severe and fatal cases of pertussis occur in infants younger than eight weeks of age, before initiation of the primary pertussis vaccine series. To help protect infants from pertussis during this vulnerable period, women are recommended to receive Tdap vaccine at the start of the third trimester of each pregnancy to optimize transplacental transfer of antibodies to the fetus. T...
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ورودعنوان ژورنال:
- Canadian family physician Medecin de famille canadien
دوره 59 5 شماره
صفحات -
تاریخ انتشار 2013